#15 Comparing Bispecific Antibody Format Feasibility (On Demand)

Not every antibody can be combined to produce well-behaved multi-specifics. The valency and geometry of each design can determine the production, target engagement and ultimately the requisite biological functions. In this case study, we selected two established antibody therapeutics, trastuzumab and a humanized OKT3 to produce 17 different bispecific formats to compare the feasibility of each format.

Seminar Information
Date Presented:
August 03, 2023 11:00 AM Eastern
Length:
1 hour
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Comparing Bispecific Antibody Format Feasibility

Not every antibody can be combined to produce well-behaved multi-specifics. The valency and geometry of each design can determine the production, target engagement and ultimately the requisite biological functions. In this case study, we selected two established antibody therapeutics, trastuzumab and a humanized OKT3 to produce 17 different bispecific formats to compare the feasibility of each format.

Speaker Information
Ed Horton  [ view bio ]
Individual topic purchase: Selected