#28 Rapid Generation of Bispecific Antibodies through Engineered Reversibly Inhibitable SpyCatcher (On Demand)

Bispecific antibodies (bsAbs) are rapidly emerging as a transformative class in biotherapeutics, offering unique mechanisms of action by simultaneously engaging two different targets. Their potential spans oncology, immunotherapy, and beyond, making their efficient and precise development a cornerstone of modern biologics research.
This webinar will delve into the innovative SpyLock technology, a groundbreaking advancement in the site-specific assembly and screening of bispecific antibodies. Leveraging the SpyCatcher-SpyTag system, SpyLock introduces a reversible locking mechanism to the SpyCatcher that can be applied to rapidly generate hundreds of bispecific antibodies for high-throughput screening of antibody pairs with optimal epitope recognition and affinity matching. Interesting candidates can then be further assessed in their final bispecific format, streamlining the identification of bispecific antibodies.

Seminar Information
Date Presented:
December 12, 2024 11:00 AM Eastern
Length:
1 hour
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#28 Rapid Generation of Bispecific Antibodies through Engineered Reversibly Inhibitable SpyCatcher (On Demand)

Bispecific antibodies (bsAbs) are rapidly emerging as a transformative class in biotherapeutics, offering unique mechanisms of action by simultaneously engaging two different targets. Their potential spans oncology, immunotherapy, and beyond, making their efficient and precise development a cornerstone of modern biologics research.
This webinar will delve into the innovative SpyLock technology, a groundbreaking advancement in the site-specific assembly and screening of bispecific antibodies. Leveraging the SpyCatcher-SpyTag system, SpyLock introduces a reversible locking mechanism to the SpyCatcher that can be applied to rapidly generate hundreds of bispecific antibodies for high-throughput screening of antibody pairs with optimal epitope recognition and affinity matching. Interesting candidates can then be further assessed in their final bispecific format, streamlining the identification of bispecific antibodies.

Speaker Information
Francisco Ylera  [ view bio ]
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On-Demand
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Individual topic purchase: Selected