Bispecific antibodies (bsAbs) are rapidly emerging as a transformative class in biotherapeutics, offering unique mechanisms of action by simultaneously engaging two different targets. Their potential spans oncology, immunotherapy, and beyond, making their efficient and precise development a cornerstone of modern biologics research.
This webinar will delve into the innovative SpyLock technology, a groundbreaking advancement in the site-specific assembly and screening of bispecific antibodies. Leveraging the SpyCatcher-SpyTag system, SpyLock introduces a reversible locking mechanism to the SpyCatcher that can be applied to rapidly generate hundreds of bispecific antibodies for high-throughput screening of antibody pairs with optimal epitope recognition and affinity matching. Interesting candidates can then be further assessed in their final bispecific format, streamlining the identification of bispecific antibodies.